YC aging, microbiome ⟷ aging, bone health and more things to read.

Healthcare through a Kentucky lens. Yeah, it's niche. But neat!

Author

Andrew Steen
July 28, 2026

Sunset is now officially before 9 PM. It’s all downhill from here.

YC Requests for Startups

Fall 2026. AI for the Aging Population.

Microbiome ⟷ aging

Interesting review article.

Microbiome remodeling during aging: Integrative multi-omics and spatiotemporal perspectives on immune and metabolic regulation - PubMed

Changes in the gut microbiota occur throughout the human lifespan, and maintaining microbial homeostasis plays a critical role in promoting healthy aging. In recent years, substantial progress has been made in elucidating the mechanistic links between aging and microbiota remodeling, highlighting th …

PubMed

Written in 2014. Yeah.

Nutrition and aging; a sub-niche for Louisville?

This tweet caught my attention in April 2014. Louisville is home to the largest concentration of nursing-home and extended-care companies in the nation. Aging Care Atria Senior Living, Inc., in par…

louisvillelifescience

Osteoporosis

Here’s a page from Prime Therapeutics' 2026 Medical Pharmacy Trend Report. My highlight of osteoporosis drugs.

Related, wrote this recently on bone health.

Bone Health and Fractures

I’ve been working on a project related to fractures. In a prior work life I looked extensively at the osteoporosis space, so fracture prevention isn’t entirely new.

www.linkedin.com/pulse/bone-health-fractures-liverpoollane-com-2v87e/?trackingId=ozrNh5fzz6NP7jTZozP%2F2Q%3D%3D

Well, well, well…

Biogen bets newly acquired Apellis can paper over Leqembi's disappointing sales into 2027

July 23, 2026 10:00 AM EDT

endpoints.news/biogen-counts-on-drugs-from-apellis-deal-to-patch-leqembis-slow-sales

VC funding for science-based startups

This paper has some interesting data.

Timing is key: Navigating venture capital funding for science-based startups

Andrea Fosfuri, Jay Prakash Nagar ; Volume 55, Issue 3, April 2026, 105402

www.sciencedirect.com/science/article/pii/S0048733325002318

“Consistent with our model, startups with more valuable technology — measured by a higher number of forward citations — tend to secure VC funding earlier.”

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