VBC, HSBC, CDS, TMC and other non-acronym nuggets of interest.

Healthcare through a Kentucky lens. Yeah, it's niche. But neat!

Author

Andrew Steen
January 13, 2026

IYKYK

VBC

Responses to a VBC survey that Health Tech Nerds ran last week. Interesting. “It’s not there yet, but heading in the right direction” was clearly the most common opinion.

I suspect we could get opinions on value-based care out of Louisville.

HSBC Venture Healthcare Report

There’s a ton of interesting data in here. I’m particularly fond of the Computational Biology Analysis.

Why then show biopharma deals? Mainly so I can note that Kentucky is South(east), not Midwest as depicted. The U.S. Census Bureau knows it. Dwight Yoakam knows it. C’mon HSBC.

Clinical decision support software is a subcategory of computational biology.

Speaking of CDS

Industry guidance just came out.

Clinical Decision Support Software - Guidance

This guidance clarifies the scope of FDA’s oversight of clinical decision support software intended for health care professionals (HCPs) as devices.

www.fda.gov/regulatory-information/search-fda-guidance-documents/clinical-decision-support-software

And speaking of industry guidance

Draft guidance.

Use of Bayesian Methodology in Clinical Trials of Drug and Biological

This draft guidance provides guidance to sponsors and applicants on the appropriate use of Bayesian methods in clinical trials.

www.fda.gov/regulatory-information/search-fda-guidance-documents/use-bayesian-methodology-clinical-trials-drug-and-biological-products

Remember “The Lab” at Apellis’ old Crestwood office? No? Well, Revon Systems operated out of the same office space and discussions of Bayesian trials occurred in and around The Lab circa 2016. Trust me.

Houston and the Texas Medical Center

This piece has a biotech and patient accrual for clinical trials slant.

But it’s also about density and intentionality.

How — and why — Houston is building a scalable life sciences ecosystem

Houston has long been recognized as a world-class medical city, anchored by the Texas Medical Center, Rice University, and other clinical care and

www.statnews.com/sponsor/2026/01/08/how-and-why-houston-is-building-a-scalable-life-sciences-ecosystem

Perhaps in 2026 I’ll write some institutional knowledge pieces on the Louisville Medical Center.

Louisville Health Innovation Meetup

Been to the new Thrive Center location yet?

Louisville Health Innovation Meetup · Luma

Interested in healthcare, healthtech, digital health, the life sciences and adjacent spaces? Real innovation happens when people show up to give, not just to…

luma.com/l9srpt1x

Register. Show up.

Want to collaborate? Sponsor something? Plan something elaborate?

Hit us up.